A Powerful Natural Antioxidant for Health and Beauty

Could Alpha Lipoic Acid Relieve Sciatica Pain and Carpal Tunnel Syndrome?

Alpha lipoic acid helps treat sciatica.

According to results of clinical studies, taking daily oral alpha lipoic acid supplements could significantly reduce pain as well as improve nerve function in 2 common conditions:


The study involved 64 adult patients suffering from acute back pain and sciatica due to a herniated disc in the spine. Patients were randomly assigned to take either 1180 mg/day of acetyl-L-carnitine or 600 mg/day of alpha lipoic acid for 60 days. (iii.20)

Clinical Trial

At the end of the 60 days, those who had taken alpha lipoic acid showed significant improvement in nerve function (as measured by electromyography). Other benefits included: (iii.20)

  • Over 50% of alpha lipoic acid patients needed less pain medication.
  • Alpha lipoic acid improved symptom scores significantly more than acetyl-L-carnitine.
Alpha lipoic acid and other vitamins and antioxidants help treat carpal tunnel syndrome.

Carpal Tunnel Syndrome

In a clinical trial involving 112 adult patients suffering from moderate to severe carpal tunnel syndrome was conducted for 90 days. Two groups of 56 patients each were randomly assigned to take 1 of 2 treatments: (iii.7)

Table III.9: Therapy Combinations Used to Treat Carpal Tunnel Syndrome
Alpha lipoic acid Combo, Twice a Day
Ingredients Dosage per Capsule
Alpha lipoic acid 300 mg
Gamma-linolenic acid 180 mg
Selenium 25 µg
Vitamin E 7.5 mg
Vitamin B1 1.05 mg
Vitamin B2 1.2 mg
Vitamin B5 4.5 mg
Vitamin B6 1.5 mg
Vitamin B Combo, Three Times a Day
Ingredients Dosage per Capsule
Vitamin B1 100 mg
Vitamin B6 150 mg
Vitamin B12 500 µg

Patients who took the alpha lipoic acid/GLA-based supplement showed significantly reduced pain and functional impairment. The group that took the multiple B-vitamins had only slightly improved symptoms and actually decreased ability to function. (iii.7)

In another 6 month clinical trial, alpha lipoic acid was combined in a nutraceutical with: (iii.142)

  • Echinacea angustifolia
  • Conjugated linoleic acid
  • Multivitamin antioxidants

The 60 patients were divided in 2 groups — one was treated only with the nutraceutical supplement, the other was treated with shock wave therapy. Both groups showed reduced symptoms and improved function within 30 days, and continued to improve over the course of the clinical study. In fact, over 88% of patients experienced good to excellent results with the supplement containing alpha lipoic acid. (iii.142)

Disclaimer: This website is not intended to replace professional consultation, diagnosis, or treatment by a licensed physician. If you require any medical related advice, contact your physician promptly. Information presented on this website is exclusively of a general reference nature. Do not disregard medical advice or delay treatment as a result of accessing information at this site.